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$549,000
60333460 MLS
Versatile commercial property situated on approximately 12.5 acres near Center Creek, offering an impressive combination of office, shop, and additional building space. The main building is equipped with 400-amp electrical service and features multiple private offices, conference room spaces, restrooms (including a shower) , a kitchenette + break area, providing plenty of room for a variety of business operations.The 40x40 attached shop area offers (3) 14ft overhead doors, 17+ foot ceiling height, and 220V power, making it well suited for a variety of needs. The property also includes a 24x44 detached building with electric, providing even more flexibility for additional workspace or storage. With substantial acreage and a combination of professional office and industrial/shop space, this property offers a unique opportunity for a wide range of commercial uses.

4204 County Lane 118, Carthage

Listing courtesy of Southtown Real Estate.

$310,000
60333026 MLS
Looking for the perfect space on Main Street in Joplin? Look no further. This space is currently used for retail. The main level is 2500 sqft and has a small deck off the back that goes into the alley. There is also access to the mezzanine on the main level that can be additional finished space or storage. There are 2 restrooms, office/storage area, storage under the stairs and a large utility room with floor sink on the main level. There is an additional 2500sqft upstairs that has 2 separate entrances to access the space. The upstairs is completely gutted and ready to be turned into something. It could fit 2 apartments or a large loft. Utilities are also reasonable. New Roof and new aweing to be installed.

120 S Main Street, Joplin

Listing courtesy of Keller Williams Realty Elevate.

$215,000
60332198 MLS
Turnkey salon space offering an excellent opportunity for an established stylist, beauty professional, or entrepreneur looking to open or expand a business. The property features a functional, inviting layout designed to accommodate salon operations, with 4 dedicated private rooms with wash bowels, 1 room that could be used for a nail studio, and 1 room designed for an esthetician. This thoughtfully designed space is complete with a comfortable waiting room, bathroom, kitchenette/break room, and laundry room. Located in a convenient setting directly off 7th street with potential for strong customer traffic, this space provides a great foundation for a successful business. The existing salon infrastructure can help minimize startup costs and reduce the time needed to become operational. Whether you're an experienced salon professional or looking for an investment opportunity, this property offers the flexibility and existing infrastructure to bring your vision to life!

622 S Park Avenue, Joplin

Listing courtesy of PRO 100 Inc., REALTORS. 417-782-0800

$359,900
60330225 MLS
Primary Home & Second Home? Rental Investment? Home Business? Income Property? The possibilities are endless with this unique property offering easy highway access!Situated on nearly 2 acres on the edge of Carthage, just outside the city limits, this property features two freestanding homes, each offering 3 bedrooms and 2 bathrooms, with a combined living area of nearly 3,500 square feet.The front home offers nearly 2,000 square feet and was extensively remodeled in January 2026. Updates include new paint, flooring, light fixtures, and a new central heating system installed the first week of January 2026. The home also features large rooms, a formal dining room, vinyl siding installed in summer 2021, and a roof installed in 2018.The back home offers approximately 1,500 square feet with 3 bedrooms and 2 bathrooms. One bathroom has been remodeled, and a new central heating system and water heater were installed in March 2025. The roof was replaced in spring 2018.Whether you're looking for multi-generational living, rental income, a home-based business, or an investment opportunity, this property offers exceptional flexibility. Please see the attached plat map.Seller is in the process of having the tree removed that recently fell on the property.

1622 &1624 W Fairview Ave Avenue, Carthage

Listing courtesy of Fathom Realty MO LLC.

$950,000
60327882 MLS
Take I-44 East from Joplin and at exit 29 Sarcoxie, property is adjacent to Maverick Convenience Store. Property borders both I-44 and Business loop 44. Property wraps around the Kum and Go Convenience Store on the West and South. 1.66 acres and 11,220 square feet ' of office,, showroom and warehouse with 6500' of mezzanine for additional storage. This location has access to city utilities- water and sewer, while located just outside of the city limits. Prime exit for development as it is the only exit with City utilities between the Joplin 249 exit and the Mount Vernon exit.. This Tract has 180' of frontage on High St. which is also known as Business Loop 44 and has two buildings connected by a hallway. Building 1 has 3720', two bathrooms, office and a showroom. Building 2 has 7500' of warehouse on the ground level and 6500' of mezzanine for additional storage, two baths, two commercial doors, one central heat and air system, one 300,000 BTU suspended heat unit and two wall mounted exhaust fans. It has possible tax credits from being located in an Enterprise Zone. The possibilities are unlimited as the is building can be used as retail, warehousing, distribution center just to name a few options. The seller will retain and easement on South border of this tract in order to be able to access two tracts to the West

2583 High Street, Sarcoxie

Listing courtesy of PRO 100 Inc., REALTORS. 417-782-0800

$350,000
60327128 MLS
Exceptional commercial development opportunity in one of Webb City's most active growth corridors. This approximately 0.46-acre C-2 zoned property offers outstanding visibility and accessibility in a high-traffic location next to McDonald's and directly across from Culver's and a major shopping center. The seller has completed the demolition and removal of the former residence, leaving a nice, level lot ready for development and eliminating a significant step for the next owner. Surrounded by established national retailers, restaurants, schools, and community amenities, the property is also near the Frisco Greenway Trail and King Jack Park, contributing to consistent daily traffic and excellent exposure. With strong potential for retail, office, restaurant, service, or investment use, this site presents a rare opportunity to secure build-ready commercial land in a thriving business district. Take advantage of the location, visibility, and long-term growth potential in one of Webb City's most desirable commercial areas.

502 S Madison Street, Webb City

Listing courtesy of Keller Williams Realty Elevate.

$399,000
60326685 MLS
Position your business for success in the heart of historic downtown Carthage! This versatile commercial property offers outstanding visibility, charming curb appeal, and endless possibilities for entrepreneurs, investors, or business owners looking to establish a presence in one of Southwest Missouri's most vibrant communities. Step inside and discover a flexible layout filled with character and functionality. Large storefront windows invite natural light throughout the space while creating an attractive display area that captures the attention of both foot and vehicle traffic. The open-concept design provides ample room for retail, office, studio, service-based businesses, or a creative mixed-use concept. Multiple workspaces and storage areas offer flexibility to adapt the property to your unique business needs. Outside, the property's prominent downtown location places you among established businesses, local shops, restaurants, community events, and attractions that draw visitors year-round. The high-visibility setting provides excellent exposure while the historic surroundings create a welcoming atmosphere customers will appreciate. Whether you're launching a new venture, expanding your current operation, or adding to your investment portfolio, this downtown commercial opportunity combines location, character, and potential in one exceptional package. Bring your vision and make this landmark property the future home of your business

328 W Central Avenue, Carthage

Listing courtesy of Keller Williams. klrw369@kw.com

$3,000
60323096 MLS
$2,000 a month lease. Positioned in one of Joplin's active commercial corridors, this 2,960 square foot freestanding commercial building offers a rare opportunity for entrepreneurs, investors, and business owners seeking a flexible space with strong redevelopment potential. Located at 1220 East 15th Street in Joplin, Missouri, the property sits on approximately 0.32 acres and benefits from convenient access to Rangeline Road and Main Street, two of the area's most recognized commercial routes. With the building now cleared and ready for its next chapter, the open interior provides a blank canvas for a variety of commercial concepts. The structure was originally designed with a commercial kitchen footprint, multiple dining areas, a bar-style serving space, and a rear loading area with access from Michigan Avenue--features that provide practical infrastructure for many operational layouts. For entrepreneurs looking to establish a presence in Southwest Missouri, this property offers both visibility and adaptability. The location and layout could support a wide range of business possibilities including a restaurant or bake shop, a retail storefront, climate-controlled storage, or specialized operations such as paint or finishing work with hood ventilation, plastics or ventilation-based production, server hosting or crypto-mining operations, or a pawn shop. With appropriate licensing and approvals, the building may also serve as a strategic location for a dispensary business, taking advantage of the strong commercial traffic in the surrounding Joplin area. Built in 1950 and connected to municipal water and sewer, the property provides the foundational utilities needed for many commercial uses while still allowing a new owner to tailor the interior to their business model. Central air, natural gas availability, and the rear loading access add further functionality for daily operations and deliveries.

1220 E 15th Street, Joplin

Listing courtesy of Venture Group Real Estate.

$750,000
60323054 MLS
A rare opportunity to own an incredible 16,500 sq. ft. multi-purpose property packed with space, functionality, and endless possibilities! Situated on 6 beautiful acres with outstanding road frontage and visibility, this one-of-a-kind property is designed to impress from the moment you walk through the doors. Featuring TWO spacious sanctuaries, a large gymnasium area, and a massive full eat-in kitchen built to host large gatherings with ease, this property is ready to serve a wide variety of needs. The stunning welcome/greeting area creates an inviting first impression, while the abundance of additional rooms offer endless flexibility for offices, classrooms, meeting spaces, childcare, storage, or future expansion opportunities. Whether you're looking for a thriving church campus, community center, private school, event venue, or investment opportunity, this property offers the size, layout, and location to bring your vision to life. Properties with this much potential and visibility are incredibly hard to find!

18715 Hyacinth Road, Carthage

Listing courtesy of Century 21 Properties Unlimited.

$849,000
60319368 MLS
Positioned for visibility, growth, and versatility, this 2,907 square foot open-span commercial space offers a rare opportunity for a wide range of business uses--including retail, office, medical, or restaurant concepts. Built in 2016, the property features a modern industrial aesthetic with polished concrete flooring and exposed ductwork, creating a clean, contemporary environment ready to be customized to your brand or operational needs. Designed with future expansion in mind, the northeast side of the building incorporates a structural beam, allowing for seamless growth. The current structure sits on the western portion of a generous 0.95-acre (41,382 square feet) lot, leaving ample room for expansion, additional parking, or further development. The exterior showcases partial stone accents, adding curb appeal and durability, while two HVAC systems provide efficient climate control throughout the space. Strategically located just off I-49, the property benefits from excellent accessibility and strong visibility, making it ideal for capturing both local clientele and out-of-town traffic. The surrounding area is a thriving commercial and residential hub, with nearby multi-family developments and a strong mix of national and local businesses, including dining, retail banking, fitness centers, medical and dental offices, dispensary, and big-box retailers. With its prime location, flexible layout, and expansion potential, this property presents endless possibilities for investors, owner-users, or developers looking to establish or grow their presence in a high-traffic, high-demand corridor.

500 Peachtree Drive, Carthage

Listing courtesy of PRO 100 Inc., REALTORS. 417-782-0800

$600,000
ARKMLS-1339326 MLS
Strategically located near Interstate 44 and the Joplin medical corridor, this highly versatile commercial property offers an exceptional opportunity for investors or owner-users seeking scale, accessibility, and adaptive reuse potential. The building features approximately 7,318 square feet with a functional layout that supports a wide range of business models including medical, professional, event, educational, or institutional use. The interior configuration includes large open areas, multiple private rooms or suites, restroom facilities, and a kitchen/breakroom component -- providing immediate usability with minimal reconfiguration required for many operations. The property's proximity to major healthcare facilities makes it particularly attractive for medical offices, outpatient services, therapy providers, or medical storage while interstate access enhances regional convenience for clients, staff, and logistics. Buyer to independently verify zoning, permitted uses, and any applicable municipal ordinances.

5734 S Main Street, Joplin

Listing courtesy of Venture Group Real Estate. 417-621-1883

$695,000
60315510 MLS
This versatile 10,800-square-foot commercial building offers an excellent opportunity for a variety of business uses in a high-visibility central Joplin location. Formerly an auto dealership, the property has successfully supported automotive sales, auto repair, tire service, and retail operations, making it well-suited for automotive, service, showroom, warehouse, or retail businesses.The building features a spacious showroom, multiple offices, and a large work area, along with seven overhead doors for easy vehicle or equipment access. Recent updates include a new roof, new exterior paint, and a new HVAC unit, reflecting consistent maintenance and pride of ownership.Positioned along a busy thoroughfare with an estimated 5,000-10,000 vehicles per day, the property provides strong visibility and accessibility. Additional highlights include an existing sign pole, ample parking, and exterior lighting, making the site ready for immediate business use.This is a rare opportunity to secure a well-maintained, flexible commercial property in one of Joplin's high-traffic corridors.

402 E 7th Street, Joplin

Listing courtesy of PRO 100 Inc., REALTORS. 417-782-0800

$1,800
60315052 MLS
Highly visible commercial property located along Joplin's heavily traveled 20th Street (S Empire Ave) corridor. Zoned C-1, this single-story building offers excellent exposure, strong traffic count, and a flexible layout ideal for owner-users or investors. The property features three exterior entrances, making it well suited for multi-tenant use, shared workspace, or a variety of commercial applications. The interior is currently configured with eight private offices, a reception window, small lobby, a large open room approximately 48' x 21', and two half baths. Additional highlights include a membrane roof and HVAC system installed approximately in 2011, rear parking (approx. 1,000 sq ft), and ample street parking. The layout and zoning allow for numerous possibilities including professional offices, insurance or administrative use, creative or collaborative space, climate-controlled storage, or potential adaptive reuse. Prime location, strong visibility, and versatile configuration make this a standout opportunity on one of Joplin's key commercial corridors. 1. HVAC and membrane roof Approx 2011 install 2. Parking 1000 sq ft rear parking Street parking 3. 20th street frontage- High visibility and traffic count 4. 3 exterior entrances Great for multi use or shared work space 5. Zoned c1 6. Currently configured with: 8 private offices Reception window Small lobby Large open room-approx. 48' x 21' Two half baths

2001 S Empire Avenue, Joplin

Listing courtesy of Venture Group Real Estate.

$175,000
60312060 MLS
Highly visible commercial property located along Joplin's heavily traveled 20th Street (S Empire Ave) corridor. Zoned C-1, this single-story building offers excellent exposure, strong traffic count, and a flexible layout ideal for owner-users or investors. The property features three exterior entrances, making it well suited for multi-tenant use, shared workspace, or a variety of commercial applications. The interior is currently configured with eight private offices, a reception window, small lobby, a large open room approximately 48' x 21', and two half baths. Additional highlights include a membrane roof and HVAC system installed approximately in 2011, rear parking (approx. 1,000 sq ft), and ample street parking. The layout and zoning allow for numerous possibilities including professional offices, insurance or administrative use, creative or collaborative space, climate-controlled storage, or potential adaptive reuse. Prime location, strong visibility, and versatile configuration make this a standout opportunity on one of Joplin's key commercial corridors. 1. HVAC and membrane roof Approx 2011 install 2. Parking 1000 sq ft rear parking Street parking 3. 20th street frontage- High visibility and traffic count 4. 3 exterior entrances Great for multi use or shared work space 5. Zoned c1 6. Currently configured with: 8 private offices Reception window Small lobby Large open room-approx. 48' x 21' Two half baths

2001 S Empire Avenue, Joplin

Listing courtesy of Venture Group Real Estate.

$599,000
60311343 MLS
Step into a remarkable piece of Joplin history with this expansive 13,000+ sq ft commercial building on a corner lot, originally constructed in 1905 and thoughtfully updated to blend modern function with historic charm. Previously utilized as a church, this property offers endless possibilities for office use, event space, studio, nonprofit, or redevelopment. Inside, you'll find 10+ private offices, 2 generous common areas, and 3 freshly remodeled bathrooms--including one equipped with a shower for added convenience. One of the standout features is the gorgeous stained-glass windows, adding a stunning touch that you won't find elsewhere. Whether you're an investor, entrepreneur, or organization looking for a one-of-a-kind space, this property provides flexibility, size, and historic beauty all in one.

1601 S Wall Avenue, Joplin

Listing courtesy of Southtown Real Estate.

$275,000
60310645 MLS
Looking for space that works as hard as you do? This commercial property offers a practical layout for a distribution hub, nonprofit,food service operation, or community outreach program--with the flexibility to adjust as your business grows. Up front, you'll find a welcoming entry and a series of private offices that can serve as meeting space, client intake, or administration. The interior is clean and comfortable, with wide hallways,solid construction, and easy access to utility systems like phone and internet--already built in and ready to go. At the heart of the building is a large multi-use room that flows into a working kitchen and break area. Whether you're hosting meetings, packing boxes, or staging equipment, there's room to move and room to grow. Toward the back, the heated and cooled warehouse space stands ready for action. Two walk-in units--one refrigeration, one freezer--are currently in place and negotiable with sale. Dock access, fenced perimeter, and dual parcel layout provide options for storage, delivery, or expansion. Need to lease part of it out down the line? You've got a natural separation already built in. This isn't a blank slate--it's a head start. And it's located on a quieter street with access to town, a sense of community, and a property layout that allows for multiple uses and partnerships. If you're ready to launch, grow, or relocate your service-focused business, come take a look. This could be the place where things finallycome together.

2307 Missouri Avenue, Carthage

Listing courtesy of Keller Williams Realty Elevate.

$1,700,000
60307716 MLS
This fully renovated commercial property blends modern technology, comfort, and versatility. Featuring 3 separate suites currently operated as one, the space can easily be divided or continue functioning as a single, cohesive operation. The building offers 7 private offices ,a welcoming lobby, a built-in reception desk, a large conference room and break room, 5 bathrooms, 2 small storage rooms, and a large open hallway. The warehouse and event space are both air-conditioned and heated, creating a comfortable environment year-round. The property is secured with a gated and fenced yard, a smart lock system with key card access, and 20+ security cameras with months of recording capability. Technology and efficiency are built in, with LED lighting conversion, smart home and motion lighting, and app-controlled garage doors for convenient operation.Additional features include all new Argon-filled exterior windows, 1 exterior loading dock, 6 covered interior loading docks, and a back deck designed for employee breaks. The property offers a total of 3 14x18 garage doors, 1 10x10, one 10x10 glass, 2 8x16 glass, 1 10x10 interior, and 6 7x8 interior garage doors. The largest office includes a 65-inch built-in smart board, while the 10-12-inch thick exterior walls provide exceptional durability and insulation.Renovated just three years ago, this property combines functionality, security, and high-end smart features, making it an excellent fit for a variety of commercial or industrial uses. Zoned M-2.

231 N Main Street, Joplin

Listing courtesy of Keller Williams Realty Elevate.

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