Mcdonald County, MO Real Estate Search

Mcdonald County, MO 5 Bedroom Homes for Sale

McDonald County, MO, offers a diverse selection of 5-bedroom homes for sale, appealing to families and buyers seeking ample space and comfort. Nestled in the picturesque Ozarks, this region is known for its stunning natural beauty, access to outdoor activities, and a close-knit community vibe. Many of the available properties feature modern amenities, spacious layouts, and sizable lots, making them ideal for both entertaining and relaxation. Buyers can find homes that boast beautiful interiors, expansive backyards, and proximity to local schools, parks, and recreational areas, ensuring a quality lifestyle in this charming part of Missouri. Whether you’re looking for a serene retreat or a vibrant family home, McDonald County has options that cater to a variety of needs and preferences.

Our website features the best real estate search for 5 bedroom homes available in Mcdonald County, MO and surrounding areas. It is the only site you will ever need! It is easy-to-use and updated by the official REALTOR®’s database every 15 minutes. 

You can save searches, and get daily email alerts of new listings, price changes, sold data, and market reports. Our Interactive Map Search allows you to view properties on a map or refine your search by drawing the boundaries around the area you desire.

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Newest Mcdonald County, MO 5 Bedroom Homes for Sale

$1,150,000
5 Beds 4 Baths 60333494 MLS
Where timeless craftsmanship meets modern country living, this extraordinary 1910 Craftsman-style residence offers a rare combination of historic character, thoughtful updates, and nearly 48 acres of scenic countryside. Fully remodeled in 2018, the home retains the architectural presence and warmth of its era while delivering the comfort and functionality today's buyers desire.Sweeping gabled rooflines, classic dormers, multi-pane windows, crisp white trim, a metal roof, mature trees, and an inviting covered front porch create striking curb appeal and a memorable first impression.Inside, the spacious main residence features 5 bedrooms and 3.5 baths with abundant room for family, guests, entertaining, or working from home. The extensive remodel blends modern conveniences with the craftsmanship and character that make century-old homes truly special.Beyond the home, nearly 48 acres offer an appealing mix of open ground and wooded terrain. Approximately 10-15% is cleared and suitable for livestock, while the remaining acreage provides excellent opportunities for hunting, recreation, trail riding, exploring, and enjoying the privacy of the outdoors. Whether envisioned as a private country estate, hobby farm, recreational retreat, or hunting property, the possibilities are exceptional.A secluded inground swimming pool and patio create a private backyard retreat perfect for relaxing or entertaining.Completing the property is an impressive 1,600-square-foot shop with 1-bedroom, 1-bath living quarters, providing outstanding flexibility for guests, extended family, hobbies, or workspace.With 6 total bedrooms, 4.5 baths, nearly 48 acres, a private pool, additional living quarters, substantial shop space, and recreational land, this remarkable property offers a lifestyle as distinctive as its history.

53 Mary Road, Anderson

Listing courtesy of Coldwell Banker Harris McHaney & Faucette.

$3,250,000
5 Beds 3 Baths 60329757 MLS
Rarely does a property of this scale and versatility come to market. 291 acres offering the perfect blend of privacy, productivity, and panoramic beauty. Located directly adjacent to the Big Sugar River, the main home features 4 bedrooms and 3 baths, with a secondary kitchen on the lower level, ideal for multigenerational living or guests. A second home is currently under construction, adding even more possibility to this exceptional estate.The land is roughly two-thirds wooded and one-third open pasture, with sweeping, panoramic views throughout. Two substantial barns anchor the working side of the property one an impressive 60x100, the other 40x60 offering ample space for equipment, hay, or livestock operations.Water resources are exceptional: beyond frontage on the Big Sugar River, the homes are serviced by a 550-foot deep well, with a secondary well and septic system at an old home site ready for future use. A cave, bluffs, natural springs and ponds dot the landscape. Well spigots are strategically placed throughout the property for herd maintenance, complemented by cross fencing for efficient rotational grazing.Whether you're envisioning a working ranch, a family compound, a recreational retreat, or all three, this property delivers the acreage, infrastructure, water, and views to make it happen. Opportunities like this with this much land, water, and improvements already in place don't come around often.

454 Green Hill Lane, Rocky Comfort

Listing courtesy of Collier & Associates-Rogers.

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The data relating to real estate for sale on this web page comes in part from the Internet Data Exchange (IDX) of the Southern Missouri Regional MLS, LLC, Inc. Real estate listings held by Brokerage firms other than our company are marked with the IDX logo and detailed information about them includes the name of the listing Brokers. The information being provided is for consumers’ personal, noncommercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The information being provided is not guaranteed, and all information should be verified by the consumer. Any representation that a web site contains all listings shall only mean that the website contains all listing available to the public through the IDX data feed. There may be other properties offered through a REALTOR® that have not been displayed on this site. © 2026 Southern Missouri Regional MLS, LLC. All rights reserved. Last Updated:


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